I'm forever trying to replicate single-cell electrophysical models in my bedroom but I normally end up just eating doughnuts and playing on the Playstation instead. I think my luck has changed though thanks to CESE. The program simulates the surroundings of electrophysical activity to aid with scientific research.
CESE works with 13 different models of study, such as Tusscher-Panfilov for human heart ventricles, Hund-Rudy for canine ventricles, plus Tusscher, Nobleman, Panfilov, and all the usual suspects. Although it's definitely not a program for newcomers to medical science, CESE is used in several university laboratories and pharmaceutical companies that analyze by means of ionic current simulations based on different conditions. The interface is a little basic but the program is capable of performing very complex simulations without draining your system resources.